Home Categories Food Additives 2-Mercaptoethanol
A8532632

2-Mercaptoethanol , 99% , 60-24-2

Synonym(s):
β-Mercaptoethanol;2-Hydroxyethylmercaptan;2-Mercaptoethanol;BME;Thioethylene glycol

CAS NO.:60-24-2

Empirical Formula: C2H6OS

Molecular Weight: 78.13

MDL number: MFCD00004890

EINECS: 200-464-6

Update time: 2022-07-08

PRODUCT Properties

Melting point: -100 °C
Boiling point: 157 °C (lit.)
Density  1.114 g/mL at 25 °C (lit.)
vapor density  2.69 (vs air)
vapor pressure  1 mm Hg ( 20 °C)
refractive index  n20/D 1.500(lit.)
FEMA  4582 | 2-HYDROXYETHANETHIOL
Flash point: 165 °F
storage temp.  Store below +30°C.
solubility  H2O: 1 mL/mL
pka 9.72(at 25℃)
form  liquid
color  Clear colorless to slightly yellow
Specific Gravity 1.119 (20/4℃)
Odor Disagreeable odor
PH Range 4.5 - 6 at 500 g/l at 20 °C
PH 4.5-6 (500g/l, H2O, 20℃)
explosive limit 2.3-18%(V)
Water Solubility  soluble
FreezingPoint  <100℃
Sensitive  Air Sensitive & Hygroscopic
λmax λ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.3
Merck  14,5869
JECFA Number 1925
BRN  773648
Stability: Air Sensitive
InChI 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
InChIKey DGVVWUTYPXICAM-UHFFFAOYSA-N
SMILES OCCS
LogP -0.20
CAS DataBase Reference 60-24-2(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2-mercapto-(60-24-2)
EPA Substance Registry System 2-Mercaptoethanol (60-24-2)
Absorption ≤0.31 at 280nm
≤1.50 at 260nm

Description and Uses

2-Mercaptoethanol is used in the preparation of nano-graphene for cellular imaging and drug delivery as well as multifunctional polymeric micelle. It acts as a reducing agent used in electrophoresis, amino acid detection, and distinguishing ssDNA/dsDNA. It is also employed as a standard buffer. It is also used in the preparation of PVC heat stabilizers and as a chain transfer agent in the manufacture of PVC. Further, it is used in some RNA isolation procedures to eliminate ribonuclease. It is utilized as a corrosion inhibitor and ore floatation agent. In biochemistry, it is useful to study the activity of the immune system. Solubilizes proteins by reducing disulfide linkages.

Safety

Symbol(GHS) 
GHS05,GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H331-H310-H315-H317-H318-H361d-H373-H410
Precautionary statements  P273-P280-P301+P310-P302+P352+P310-P304+P340+P311-P305+P351+P338
target organs Liver,Heart
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  T,N
Risk Statements  20/22-24-34-51/53-36/37/38-22-23/24/25-50/53-48/22-43-41-38
Safety Statements  26-36/37/39-45-61-29-23-27-60
RIDADR  UN 2966 6.1/PG 2
WGK Germany  3
RTECS  KL5600000
3-10-13-23
Autoignition Temperature 295 °C
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  II
HS Code  29309070
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 2
Eye Dam. 1
Repr. 2
Skin Irrit. 2
Skin Sens. 1A
STOT RE 2 Oral
Hazardous Substances Data 60-24-2(Hazardous Substances Data)
Limited Quantities 100ml (liquid) or 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)

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