3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline , 98+% , 154057-56-4

CAS NO.：154057-56-4

Empirical Formula: C19H15BrFN

Molecular Weight: 356.23

MDL number: MFCD09031391

EINECS: 686-743-7

PRODUCT Properties

• Melting point: 131-134°C
• Boiling point: 467.6±45.0 °C(Predicted)
• Density: 1.461±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
• pka: 4.32±0.50(Predicted)
• form: Solid
• color: White to Off-White
• InChI: InChI=1S/C19H15BrFN/c20-11-16-18(12-7-9-14(21)10-8-12)15-3-1-2-4-17(15)22-19(16)13-5-6-13/h1-4,7-10,13H,5-6,11H2
• InChIKey: QCNHMJKMLPPGMF-UHFFFAOYSA-N
• SMILES: N1C2C(=CC=CC=2)C(C2=CC=C(F)C=C2)=C(CBr)C=1C1CC1

Description and Uses

3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338