Pyrazolo[1,5-a]pyridine , 97% , 274-56-6

CAS NO.：274-56-6

Empirical Formula: C7H6N2

Molecular Weight: 118.14

MDL number: MFCD08752622

PRODUCT Properties

• Boiling point: 37-39℃/0.2mm
• Density: 1.14±0.1 g/cm3(Predicted)
• refractive index: 1.6075
• storage temp.: Sealed in dry,Room Temperature
• pka: 2.83±0.30(Predicted)
• form: Liquid
• color: Colorless to red or brown
• InChI: InChI=1S/C7H6N2/c1-2-6-9-7(3-1)4-5-8-9/h1-6H
• InChIKey: DVUBDHRTVYLIPA-UHFFFAOYSA-N
• SMILES: C12=CC=NN1C=CC=C2

Description and Uses

Pyrazolo[1,5-a]pyridines, a class of fused heteroaromatic bicyclic compounds, have been investigated for their pharmacological and biological activities. They are used as dopamine D2/D3/D4 antagonists, anti-herpetic agents, p38 kinase inhibitors, PI3 kinase inhibitors, antitubercular agents, EP1 receptor antagonists, 5HT3-antagonists, melatonin receptor (MT1/MT2) ligands, Mcl-1Bcl-xL dual inhibitors, and corticotropin-releasing factor 1 antagonists. Pyrazolo[1,5-a]pyridine has been used as a fluorophore in the research of Zhang et al. and exhibited high quantum yield (0.64, pH 2.4), high selectivity and sensitivity, and extremely short response time[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• HS Code: 2933399990