2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol , 95% , 274693-26-4

CAS NO.：274693-26-4

Empirical Formula: C26H32F2N6O4S

Molecular Weight: 562.63

MDL number: MFCD23160137

EINECS: 682-426-2

PRODUCT Properties

• Melting point: 52 - 60°C
• Boiling point: 759.1±70.0 °C(Predicted)
• Density: 1.59±0.1 g/cm3 (20 ºC 760 Torr)
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• pka: 14.33±0.10(Predicted)
• form: Solid
• color: White to Pale Beige
• Stability: Hygroscopic
• InChIKey: WLEOHEIRUFTYCF-FYEBJQQMSA-N
• SMILES: C(O)CO[C@@H]1[C@]2([H])[C@]([H])([C@H](N3C4C(N=N3)=C(N[C@@H]3C[C@H]3C3=CC=C(F)C(F)=C3)N=C(SCCC)N=4)C1)OC(C)(C)O2

Description and Uses

2-[[(3aS,4R,6S,6aa)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol is an intermediate in the synthesis of Ticagrelor (T437700) which is an anticoagulant.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338