BD0418553
6,7-Dimethoxy-N-phenylquinazolin-4-amine , 97% , 21561-09-1
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB767.20 | In Stock |
|
| 250mg | RMB1304.00 | In Stock |
|
| 1g | RMB3390.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 441.2±40.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml |
| form | A crystalline solid |
| pka | 6.19±0.70(Predicted) |
| color | White to off-white |
Description and Uses
WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.
4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).
