8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione , 99+% , 853029-57-9

CAS NO.：853029-57-9

Empirical Formula: C20H17BrN6O2

Molecular Weight: 453.29

MDL number: MFCD18642578

EINECS: 922-028-0

PRODUCT Properties

• Melting point: >255°C (dec.)
• Boiling point: 602.9±65.0 °C(Predicted)
• Density: 1.55
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly, Heated, Sonicated)
• pka: 2.34±0.50(Predicted)
• form: Solid
• color: White to Pale Yellow
• InChI: InChI=1S/C20H17BrN6O2/c1-4-5-10-26-16-17(24-19(26)21)25(3)20(29)27(18(16)28)11-15-22-12(2)13-8-6-7-9-14(13)23-15/h6-9H,10-11H2,1-3H3
• InChIKey: RCZJXCXNYGHNSR-UHFFFAOYSA-N
• SMILES: N1(CC#CC)C2=C(N(C)C(=O)N(CC3=NC(C)=C4C(=N3)C=CC=C4)C2=O)N=C1Br

Description and Uses

8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.