4-Oxo-tempo , 98% , 2896-70-0

Synonym(s):
4-Oxo-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical

CAS NO.：2896-70-0

Empirical Formula: C9H16NO2*

Molecular Weight: 170.23

MDL number: MFCD00006187

EINECS: 220-778-7

PRODUCT Properties

• Melting point: 33-38 °C
• Boiling point: 299.88°C (rough estimate)
• Density: 1.0710 (rough estimate)
• vapor pressure: 2.254Pa at 25℃
• refractive index: 1.4640 (estimate)
• storage temp.: 2-8°C
• solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
• form: Needles, Crystals or Crystalline Powder
• color: Orange
• Water Solubility: Soluble in water (partly), acetone, DMSO, 100% ethanol, and diethylether. Insoluble in water.
• BRN: 1818579
• LogP: 0.28 at 22℃
• CAS DataBase Reference: 2896-70-0(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo-(2896-70-0)
• EPA Substance Registry System: 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo- (2896-70-0)

Description and Uses

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.

Free-radical nitroxide spin probe typically used for:

• Redox sources for anodes in lithium secondary batteries
• Free-radical biological studies
• Radical spin-trapping
• Electron paramagnetic resonance studies
• Polymer chemisty and synthesis applications

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H400
• Precautionary statements: P273
• Risk Statements: 36/37/38
• Safety Statements: 24/25
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: TN9200000
• TSCA: Yes
• HazardClass: 9
• HS Code: 29333990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)