Bismuth(III)citrate , 99+% , 813-93-4

Synonym(s):
Bismuth citrate;Bismuth(III) citrate

CAS NO.：813-93-4

Empirical Formula: C6H5BiO7

Molecular Weight: 398.08

MDL number: MFCD00050817

EINECS: 212-390-1

Pack Size	Price	Stock	Quantity
25g	RMB24.00	In Stock
100g	RMB51.20	In Stock
500g	RMB159.20	In Stock
1000g	RMB284.00	In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point:	300 °C (dec.) (lit.)
Density	0.94 g/mL at 25 °C (lit.)
vapor pressure	0Pa at 20℃
storage temp.	-20°C Freezer
solubility	Water (Very Slightly)
form	Crystalline Powder
color	White
Water Solubility	Insoluble in water, alcohol, ether. Soluble in ammonia solution and in solution of alkali citrates. Typical tap density 0.50g/cm^3.Soluble in ammonia, alkali citrates. Insoluble in water, alcohol and ether.
Sensitive	Light Sensitive
Cosmetics Ingredients Functions	BUFFERING CHELATING HAIR DYEING
InChI	InChI=1S/C6H8O7.Bi.3H/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;
InChIKey	FNVSCXCYBVACNW-UHFFFAOYSA-N
SMILES	C(O)(C(=O)O)(CC(=O)O)CC(=O)O.[BiH3]
LogP	-0.37 at 25℃
CAS DataBase Reference	813-93-4(CAS DataBase Reference)
EPA Substance Registry System	1,2,3-Propanetricarboxylic acid, 2-hydroxy-, bismuth(3+) salt (1:1) (813-93-4)

Description and Uses

Bismuth subcitrate, a complex of citrate and bismuth at a molar ratio of 2:1, commercially available as tri-potassium bismuth subcitrate (CAS 57644-54-9), molecular formula C12H10BiK3O14. In particular, this substance is sometimes mixed up with bismuth citrate in the open literature and also in the dossier and some of the studies provided.
Colloidal bismuth citrate or colloidal bismuth subcitrate (CBS), a polyanionic structure of [Bi(cit)2Bi]n2n, which is commercially used in pharmaceutical preparations (see Functions and Uses) (Ref. 1). The reported bismuth content of CBS is 35.5% (Ref. 65, Tab.2); in another reference, 36.0% bismuth content was found (ref 63).
Ranitidine bismuth citrate (Tritec® and Pylorid® GSK), a pharmaceutical preparation consisting of colloidal bismuth subcitrate and ranitidine molecules encased in the crystal latter.
ref 1, Yang N, Sun H (2007) Biocoordination chemistry of Bismuth: Recent Advances. Coordination Chemistry Reviews,251, (17-20), 2354-2366
ref 63, Dresow B et al. (1991). Bioavailability of bismuth from 205Bi-labelled pharmaceutical oral Bi-preparations in rats Arch Toxicol, 65(8):646-50
ref 65, Slikkerveer A, Helmich R B, van der Voet G B, de Wolff FA. Absorption of bismuth from several bismuth compounds during in vivo perfusion of rat small intestine. J Pharm Sci. 1995 Apr 84 (4) 512-5

Bismuth citrate is used as a progressive hair dye in cosmetics. It is used as antimicrobial agents for syphills, colitis, wound infection, quartan malaria, dyspepsia and peptic ulcers.