BD0857745
Ethyl6-oxo-1,6-dihydropyrimidine-5-carboxylate , 98% , 4786-52-1
Pack Size | Price | Stock | Quantity |
1g | RMB83.20 | In Stock |
|
5g | RMB245.60 | In Stock |
|
25g | RMB995.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 185-186 °C |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
pka | 7.70±0.40(Predicted) |
Appearance | Light yellow to yellow Solid |
InChI | InChI=1S/C7H8N2O3/c1-2-12-7(11)5-3-8-4-9-6(5)10/h3-4H,2H2,1H3,(H,8,9,10) |
InChIKey | PLMIZYMXBHSARX-UHFFFAOYSA-N |
SMILES | C1NC(=O)C(C(OCC)=O)=CN=1 |
Description and Uses
7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists.
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H335-H302-H315-H319 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
HazardClass | IRRITANT |
HS Code | 2933599590 |