BD1133132
2,6-Difluoro-3-nitrobenzoic acid , 98% , 83141-10-0
| Pack Size | Price | Stock | Quantity |
| 1g | RMB24.00 | In Stock |
|
| 5g | RMB62.40 | In Stock |
|
| 10g | RMB115.20 | In Stock |
|
| 25g | RMB228.80 | In Stock |
|
| 100g | RMB773.60 | In Stock |
|
| 500g | RMB2975.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 92-96°C |
| Boiling point: | 335.5±42.0 °C(Predicted) |
| Density | 1.661 |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 1.48±0.29(Predicted) |
| color | White to Light yellow |
| InChI | InChI=1S/C7H3F2NO4/c8-3-1-2-4(10(13)14)6(9)5(3)7(11)12/h1-2H,(H,11,12) |
| InChIKey | PDDHSNODMFIIRV-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=C(F)C=CC([N+]([O-])=O)=C1F |
| CAS DataBase Reference | 83141-10-0(CAS DataBase Reference) |
Description and Uses
2,6-Difluoro-3-nitrobenzoic acid is a benzoic acid derivative that contains reactive substituent fluorine atoms and nitro groups in its molecular structure. The substance is mainly used as a reagent for organic synthesis or as a component of pharmaceutical intermediates. It is used in the synthesis of B-Raf kinase inhibitors, such as vemurafenib, which causes programmed cell death (apoptosis) in melanoma cell lines. In addition, it is used in the synthesis of fluoroquinolone antibacterial agents.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39-24/25 |
| Hazard Note | Irritant/Keep Cold |
| HazardClass | IRRITANT |
| HS Code | 29163990 |
