BD1637348
2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile , 95+% , 1240948-72-4
CAS NO.：1240948-72-4
Empirical Formula: C11H6ClFN2
Molecular Weight: 220.63
MDL number: MFCD28404592
| Pack Size | Price | Stock | Quantity |
| 1g | RMB3970.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 403.0±45.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 12.88±0.50(Predicted) |
| Appearance | Off-white to brown Solid |
| InChI | InChI=1S/C11H6ClFN2/c12-11-7(6-14)5-10(15-11)8-3-1-2-4-9(8)13/h1-5,15H |
| InChIKey | YTRFYXSOSNPMDK-UHFFFAOYSA-N |
| SMILES | N1C(C2=CC=CC=C2F)=CC(C#N)=C1Cl |
Description and Uses
2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is an important pharmaceutical intermediate. It can be used in the preparation of vorexanol fumarate and vonoprazan, and can also be used as a chemical raw material for the synthesis of other organic compounds.
2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile (Vonoprazan Impurity 33) is an impurity of Vonoprazan, a potassium-competitive acid blocker (P-CAB) that suppresses gastric acid secretion.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
