Flecainide , 95% , 54143-55-4

CAS NO.：54143-55-4

Empirical Formula: C17H20F6N2O3

Molecular Weight: 414.34

MDL number: MFCD00864713

EINECS: 685-650-9

PRODUCT Properties

• Melting point: 105-1070C
• Boiling point: 434.9±45.0 °C(Predicted)
• Density: 1.286±0.06 g/cm3(Predicted)
• Flash point: 9℃
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: pKa 9.3 (Uncertain)
• color: White to Off-White
• BCS Class: 1 or 2?
• Major Application: clinical testing
• InChI: 1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)
• InChIKey: DJBNUMBKLMJRSA-UHFFFAOYSA-N
• SMILES: O=C(NCC1CCCCN1)C2=CC(OCC(F)(F)F)=CC=C2OCC(F)(F)F
• CAS DataBase Reference: 54143-55-4(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, n-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-(54143-55-4)

Description and Uses

From the chemical point, flecainide is an analog of procainamide, to which a 2.2.2-trifluoroethoxyl group was added at C2 and C3 of the benzene ring, and a diaminoethyl side chain is ended in the piperidine ring.

Flecainide is an antiarrhythmic (class IC).

Safety

• Symbol(GHS): GHS02,GHS06,GHS08
• Signal word: Danger
• Hazard statements: H225-H301+H311+H331-H370
• Precautionary statements: P210-P260-P280-P301+P310-P311
• target organs: Eyes,Central nervous system
• Hazard Codes: F,T
• Risk Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: 3249
• WGK Germany: 1
• HazardClass: 6.1(b)
• PackingGroup: III
• Storage Class: 3 - Flammable liquids
• Hazard Classifications: Acute Tox. 3 Dermal; Acute Tox. 3 Inhalation; Acute Tox. 3 Oral; Flam. Liq. 2; STOT SE 1