Home Categories N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
BD3204845

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine , 97% , 179552-74-0

CAS NO.:179552-74-0

Empirical Formula: C15H10ClFN4O3

Molecular Weight: 348.72

MDL number: MFCD27975589

EINECS: 207-985-8

Pack Size Price Stock Quantity
250mg RMB144.80 In Stock
1g RMB362.40 In Stock
5g RMB1096.00 In Stock
10g RMB1768.80 In Stock
25g RMB3542.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 515.5±50.0 °C(Predicted)
Density  1.529±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
pka 5.07±0.70(Predicted)

Description and Uses

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Safety

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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