Home Categories Biochemical Engineering AZD5438
BD3276945

AZD5438 , 99% , 602306-29-6

Synonym(s):
4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine;AZD 5438;AZD-5438

CAS NO.:602306-29-6

Empirical Formula: C18H21N5O2S

Molecular Weight: 371.46

MDL number: MFCD11112135

Pack Size Price Stock Quantity
5mg RMB284.80 In Stock
10mg RMB426.40 In Stock
50mg RMB1406.40 In Stock
100mg RMB2109.60 In Stock
250mg RMB3164.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 655.2±65.0 °C(Predicted)
Density  1.31
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥42.1 mg/mL in EtOH
form  solid
pka 4.08±0.50(Predicted)
color  White to light yellow
InChI InChI=1S/C18H21N5O2S/c1-12(2)23-13(3)20-11-17(23)16-9-10-19-18(22-16)21-14-5-7-15(8-6-14)26(4,24)25/h5-12H,1-4H3,(H,19,21,22)
InChIKey WJRRGYBTGDJBFX-UHFFFAOYSA-N
SMILES C1(NC2=CC=C(S(C)(=O)=O)C=C2)=NC=CC(C2N(C(C)C)C(C)=NC=2)=N1

Description and Uses

AZD 5438 is a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, which leads to leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H401
Precautionary statements  P273-P501

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