Home Categories Biochemical Engineering AZD5438
BD3276945

AZD5438 , 99% , 602306-29-6

Synonym(s):
4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine;AZD 5438;AZD-5438

CAS NO.:602306-29-6

Empirical Formula: C18H21N5O2S

Molecular Weight: 371.46

MDL number: MFCD11112135

Pack Size Price Stock Quantity
5mg RMB284.80 In Stock
10mg RMB426.40 In Stock
50mg RMB1406.40 In Stock
100mg RMB2109.60 In Stock
250mg RMB3164.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 655.2±65.0 °C(Predicted)
Density  1.31
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥42.1 mg/mL in EtOH
form  solid
pka 4.08±0.50(Predicted)
color  White to light yellow
InChI InChI=1S/C18H21N5O2S/c1-12(2)23-13(3)20-11-17(23)16-9-10-19-18(22-16)21-14-5-7-15(8-6-14)26(4,24)25/h5-12H,1-4H3,(H,19,21,22)
InChIKey WJRRGYBTGDJBFX-UHFFFAOYSA-N
SMILES C1(NC2=CC=C(S(C)(=O)=O)C=C2)=NC=CC(C2N(C(C)C)C(C)=NC=2)=N1

Description and Uses

AZD 5438 is a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, which leads to leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.

Safety

Hazard statements  H401
Precautionary statements  P273-P501

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