2-((4-Fluorophenyl)sulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one , 95% , 272786-64-8

CAS NO.：272786-64-8

Empirical Formula: C13H15FN2O3S

Molecular Weight: 298.333

MDL number: MFCD20526948

EINECS: 1532714-185-1

PRODUCT Properties

• Boiling point: 479.5±55.0 °C(Predicted)
• Density: 1.47±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 1 mg/ml
• form: A solid
• pka: -0.82±0.20(Predicted)
• color: White to off-white

Description and Uses

Unifiram (DM-232) is structurally similar to Sunifiram, and is a highly potent AMPAkine-line compound with effective cognition-enhancing and anti-amnesiac effects in animal models. Although sometimes grouped with racetam compounds, Unifiram is technically not a racetam due to the broken pyrrolidone backbone.
Animal research has shown that Unifiram has a significantly greater Nootropic potency than Piracetam or Phenylpiracetam. Unifiram is shares structural similarities to Sunifiram. Animal models show similar modes of action for both compounds – increased cognitive performance and anti-amnesiac effects through interactions with the glutamatergic system and particularly through AMPA-receptor activation.

Unifiram is a highly potent AMPAkine-like nootropic with antiamnesic and cognition-enhancing effects in animal studies at up to three orders of magnitude higher potency than piracetam.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501