sec-Butyl2-(2-hydroxyethyl)piperidine-1-carboxylate , 98% , 119515-38-7

CAS NO.：119515-38-7

Empirical Formula: C12H23NO3

Molecular Weight: 229.32

MDL number: MFCD01756488

EINECS: 423-210-8

PRODUCT Properties

• Melting point: <-170°
• Boiling point: 2800C
• Density: d20 1.07
• refractive index: nD20 1.4717
• Flash point: 142°C
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Oil
• pka: 15.15±0.10(Predicted)
• color: Colourless
• InChI: InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3
• InChIKey: QLHULAHOXSSASE-UHFFFAOYSA-N
• SMILES: N1(C(OC(C)CC)=O)CCCCC1CCO
• CAS DataBase Reference: 119515-38-7
• EPA Substance Registry System: Icaridin (119515-38-7)

Description and Uses

Picaridin is an insect repellent. It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC₅₀s = 1,452 and 1,911 μM, respectively). Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay. It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m² on nets surrounding guinea pig cages. Formulations containing picaridin have been used as insect repellents against flies, mosquitoes, chiggers, ticks, and fleas.

Insect repellent.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazardous Substances Data: 119515-38-7(Hazardous Substances Data)
• Toxicity: LD50 in rats (mg/kg): 4743 orally; >2000 dermally (Yap); LC50 in rainbow trout (96 hr): 173 mg/l; in bobwhite quail (5 day diet): >5000 ppm a.i. in diet (WHO).