BD4842541
1-Bromo-3,6,9,12-tetraoxapentadecan-15-oicacid , 97% , 1393330-38-5
CAS NO.：1393330-38-5
Empirical Formula: C11H21BrO6
Molecular Weight: 329.18
MDL number: MFCD22574799
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB327.20 | In Stock |
|
| 250mg | RMB656.00 | In Stock |
|
| 1g | RMB1628.80 | In Stock |
|
| 5g | RMB4978.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 426.9±40.0 °C(Predicted) |
| Density | 1.352±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Description and Uses
Bromo-PEG4-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Bromo-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
