Perfluorophenyldiphenylphosphinate , 95% , 138687-69-1

Synonym(s):
Diphenylphosphinic acid pentafluorophenyl ester;FDPP

CAS NO.：138687-69-1

Empirical Formula: C18H10F5O2P

Molecular Weight: 384.24

MDL number: MFCD00192380

EINECS: 1308068-626-2

PRODUCT Properties

• Melting point: 47-50 °C (lit.)
• Boiling point: 413.1±55.0 °C(Predicted)
• Density: 1.45
• storage temp.: Sealed in dry,Room Temperature
• form: solid
• Appearance: White to off-white Solid
• InChI: InChI=1S/C18H10F5O2P/c19-13-14(20)16(22)18(17(23)15(13)21)25-26(24,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H
• InChIKey: OOWSDKUFKGVADH-UHFFFAOYSA-N
• SMILES: P(C1=CC=CC=C1)(C1=CC=CC=C1)(OC1=C(F)C(F)=C(F)C(F)=C1F)=O

Description and Uses

FDPP can be used as a coupling reagent in the:

• Synthesis of peptides by solid-phase and solution-phase reactions.
• Preparation of macrocyclic peptide cyclotheonamide B as a thrombin inhibitor.
• Cyclooligomerization of N-methylated-L-valine thiazole amino acid to obtain its cyclic tetramers.
• Macrocyclization of an intermediate for the total synthesis of ziziphine N , and for the macrolactamization of precursor in synthesizing cryptophycin D.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P302+P352-P304+P340
• Safety Statements: 24/25
• RIDADR: UN2811
• WGK Germany: 3
• HazardClass: 6.1
• HS Code: 29319090
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)