BD4943441
SGC0946 , 98% , 1561178-17-3
Synonym(s):
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea;5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-7H-Pyrrolo[2,3-d]pyrimidin-4-amine
CAS NO.：1561178-17-3
Empirical Formula: C28H40BrN7O4
Molecular Weight: 618.57
MDL number: MFCD26523136
EINECS: 808-588-8
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB1097.60 | In Stock |
|
| 50mg | RMB1646.40 | In Stock |
|
| 100mg | RMB2469.60 | In Stock |
|
| 250mg | RMB4197.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 125-126o C |
| Boiling point: | 771.5±60.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble20mg/mL, clear |
| pka | 12.39±0.70(Predicted) |
| form | powder |
| color | white to beige |
| InChIKey | IQCKJUKAQJINMK-AZXARCNZNA-N |
| SMILES | N(CCCN(C[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=C(Br)C3=C(N)N=CN=C32)O1)C(C)C)C(NC1=CC=C(C(C)(C)C)C=C1)=O |&1:6,7,9,11,r| |
Description and Uses
SGC0946 is a potent DOT1L methyltransferase inhbiitor used in the treatment of leukemia seen effectively in vitro.
