Oseltamiviracid , 98+% , 187227-45-8

Synonym(s):
(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylic acid

CAS NO.：187227-45-8

Empirical Formula: C14H24N2O4

Molecular Weight: 284.35

MDL number: MFCD00953940

PRODUCT Properties

• Melting point: 183-185°C
• Boiling point: 508.7±50.0 °C(Predicted)
• Density: 1.15±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,2-8°C
• solubility: ≥14.2 mg/mL in DMSO; ≥46.1 mg/mL in H2O with gentle warming; ≥97 mg/mL in EtOH with gentle warming
• pka: 4.13±0.60(Predicted)
• form: Solid
• color: White to off-white
• Major Application: pharmaceutical (small molecule)
• InChI: InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
• InChIKey: NENPYTRHICXVCS-YNEHKIRRSA-N
• SMILES: C1(C(O)=O)C[C@H](N)[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=1
• EPA Substance Registry System: 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- (187227-45-8)

Description and Uses

Oseltamivir (GS-4104) is an antiviral prodrug targeted against the influenza viruses. Oseltamivir acid is the active metabolite of oseltamivir. It acts as an inhibitor of influenza neuraminidases A and B (IC₅₀ = 0.1 to 4.9 nM for both enzymes), in this way preventing virus budding and release.

Oseltamivir Acid is a metabolite of Oseltamivir (O701000).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• WGK Germany: WGK 3
• HS Code: 9999999999
• Storage Class: 11 - Combustible Solids