3-O-Methylquercetin , 98+% , 1486-70-0
Synonym(s):
5,7,3′ ,4′ -Tetrahydroxy-3-methoxyflavone;Quercetin 3-O-methyl ether
CAS NO.：1486-70-0
Empirical Formula: C16H12O7
Molecular Weight: 316.26
MDL number: MFCD00210588
EINECS: 200-258-5
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1220.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 275 °C |
| Boiling point: | 643.0±55.0 °C(Predicted) |
| Density | 1.69±0.1 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| pka | 6.31±0.40(Predicted) |
| color | Yellow |
| BRN | 324509 |
| Stability: | Hygroscopic |
| InChI | InChI=1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3 |
| InChIKey | WEPBGSIAWZTEJR-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1OC |
| LogP | 2.020 (est) |
Description and Uses
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.
A metabolite of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells.
