Oxacillin Sodium Monohydrate , 98% , 7240-38-2

Synonym(s):
Oxacillin sodium salt monohydrate

CAS NO.：7240-38-2

Empirical Formula: C19H18N3NaO5S

Molecular Weight: 423.42

MDL number: MFCD00167146

EINECS: 629-150-0

PRODUCT Properties

• Melting point: 188 C
• Boiling point: 687℃
• alpha: D20 +201° (c = 1 in water)
• refractive index: 205 ° (C=1, H2O)
• Flash point: >110°(230°F)
• storage temp.: Inert atmosphere,2-8°C
• solubility: Freely soluble in water, soluble in methanol, practically insoluble in methylene chloride.
• form: Solid
• color: White to Almost white
• PH: pH (30g/l, 25℃) : 4.5～7.5
• Water Solubility: Freely soluble in water
• Merck: 14,6904
• BRN: 4287093
• Major Application: clinical testing
• InChIKey: ZVIYWUUZWWBNMB-VICXVTCVSA-M
• SMILES: C([C@H]1C(S[C@]2([H])[C@@H](C(N21)=O)NC(C1=C(ON=C1C1C=CC=CC=1)C)=O)(C)C)(=O)[O-].[Na+].O
• CAS DataBase Reference: 7240-38-2(CAS DataBase Reference)

Description and Uses

Oxacillin was synthesized by Bristol-Myers Laboratories in 1961 starting with 6-aminopenicillanic acid. It was the first orally active and penicillinase-stable semisynthetic penicillin to be introduced clinically. Oxacillin is slightly less stable against gastric acid and shows a lower serum concentration than phenoxymethylpenicillin, but it is highly active against phenoxymethylpenicillinresistant Staphylococcus aureus. Oxacillin has been used by oral and intramuscular administration for therapy of respiratory tract, urinary tract, gynecological, and other infections caused by benzylpenicillin-resistant bacteria.

Penicillin antibacterial.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H315-H317-H319-H334-H335
• Precautionary statements: P280g-P342+P311a-P501a-P261-P280-P284-P304+P340-P305+P351+P338-P342+P311-P280a-P405
• PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Hazard Codes: Xn,Xi
• Risk Statements: 36/37/38-42/43
• Safety Statements: 22-26-36/37
• WGK Germany: 3
• HS Code: 29411099
• Storage Class: 11 - Combustible Solids
• Toxicity: LD50 orally in rats: >8000 mg/kg (Goldenthal)