2,5-Dioxopyrrolidin-1-yl 2-cyanoacetate , 97% , 56657-76-2

CAS NO.：56657-76-2

Empirical Formula: C7H6N2O4

Molecular Weight: 182.13

MDL number: MFCD00798802

EINECS: 1592732-453-0

PRODUCT Properties

• Boiling point: 336.1±44.0 °C(Predicted)
• Density: 1.46±0.1 g/cm3(Predicted)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: DMSO (Slightly)
• pka: 0.74±0.10(Predicted)
• form: solid
• color: White
• Stability: Very Moisture Sensitive
• InChI: InChI=1S/C7H6N2O4/c8-4-3-7(12)13-9-5(10)1-2-6(9)11/h1-3H2
• InChIKey: OZLIBRFWDOSHRS-UHFFFAOYSA-N
• SMILES: C(ON1C(=O)CCC1=O)(=O)CC#N

Description and Uses

Cyanoacetic Acid N-Hydroxysuccinimide Ester is used as a pharmaceutical intermediate. It is used in the preparation of substituted pyrrolopyrimidinamines as selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• HS Code: 2933998090