BD8455431
4-Oxo-2-azetidinecarboxylic acid , 95% , 98019-65-9
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB669.60 | In Stock |
|
| 1g | RMB1765.60 | In Stock |
|
| 5g | RMB7104.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 489.4±38.0 °C(Predicted) |
| Density | 1.519±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 3.19±0.20(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C4H5NO3/c6-3-1-2(5-3)4(7)8/h2H,1H2,(H,5,6)(H,7,8) |
| InChIKey | YSPMLLKKKHCTBN-UHFFFAOYSA-N |
| SMILES | N1C(=O)CC1C(O)=O |
Description and Uses
4-Oxoazetidine-2-carboxylic acid may be interpreted as a cyclic mimetic of the amino acid Asp. Due to the high reactivity of the four-membered ring, this molecule can serve as an “electrophilic trap” in reactions with nucleophiles. 4-oxoazetidine-2-carboxylic acid can be used as a building block for developing enzyme inhibitors, particularly protease inhibitors. It undergoes coupling reactions with amino acids and oligopeptide esters. Following desilylation of the amino acid residue and deprotection, free β-lactam peptides are obtained[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| HazardClass | IRRITANT |