(2R,3S)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate , 95% , 112741-49-8

Synonym(s):
tert-Butyl (2R,3S)-(−)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

CAS NO.：112741-49-8

Empirical Formula: C21H23NO4

Molecular Weight: 353.41

MDL number: MFCD00074955

PRODUCT Properties

• Melting point: 206 °C (dec.)(lit.)
• alpha: -87 º (c=5.5 in methylene chloride)
• Boiling point: 509.6±50.0 °C(Predicted)
• Density: 1.175±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Acetone (Slightly, Heated, Sonicated), Chloroform (Slightly), DMSO (Slightly, Sonicated)
• pka: -3.28±0.60(Predicted)
• form: Solid
• color: White to Off-White
• optical activity: [α]25/D 87°, c = 5.5 in methylene chloride
• InChI: InChI=1S/C21H23NO4/c1-21(2,3)26-20(24)22-14-17(23)25-19(16-12-8-5-9-13-16)18(22)15-10-6-4-7-11-15/h4-13,18-19H,14H2,1-3H3/t18-,19+/m0/s1
• InChIKey: MRUKRSQUUNYOFK-RBUKOAKNSA-N
• SMILES: N1(C(OC(C)(C)C)=O)CC(=O)O[C@H](C2=CC=CC=C2)[C@@H]1C1=CC=CC=C1

Description and Uses

Tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and colla gen cross-link pyridinolines.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• HS Code: 2934999090