PRODUCT Properties
| Melting point: | 106-108℃ |
| Boiling point: | 175 °C(Press: 20 Torr) |
| Density | 1.127±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 15.92±0.40(Predicted) |
| Appearance | off-white solid |
Description and Uses
3-Aminopyrrolidin-2-one (cas# 2483-65-0) is used in the preparation of conformationally restricted inhibitors of angiotensin-converting enzyme. It is also used in the preparation of 2-aminoquinolines as melanin concentrating hormone receptor (MCH-1R) antagonists. Additionally, it is used in the preparation of cycloalkyl, lactam, lactone, and related compounds for inhibiting β-??amyloid peptide release and/or its synthesis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Risk Statements | 22 |
| RIDADR | UN3259 |
| HazardClass | 8 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
