N-Boc-cis-4-Hydroxy-D-proline , 95% , 135042-12-5

Synonym(s):
(2R,4R)-N-Boc-4-hydroxy-2-pyrrolidinecarboxylic acid

CAS NO.：135042-12-5

Empirical Formula: C10H17NO5

Molecular Weight: 231.25

MDL number: MFCD02094407

EINECS: 621-971-2

PRODUCT Properties

• Melting point: 146-151 °C
• alpha: +48～+52°(c=0.67,MeOH,24℃)
• Boiling point: 390.9±42.0 °C(Predicted)
• Density: 1.312
• storage temp.: 2-8°C
• form: powder to crystal
• pka: 3.80±0.40(Predicted)
• color: White to Light yellow
• optical activity: [α]22/D +50.0°, c = 1 in methanol
• InChIKey: BENKAPCDIOILGV-RNFRBKRXSA-N

Description and Uses

N-Boc-cis-4-hydroxy-D-proline can be used:

• As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
• In the synthesis of biologically important macrocyclic dilactones.
• As an intermediate in the synthesis of histamine H₃?receptor antagonists.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319
• Precautionary statements: P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900