N-Cbz-L-histidine , 98% , 14997-58-1

Synonym(s):
N_α-Carbobenzyloxy-L-histidine;N_α-Z-L-Histidine

CAS NO.：14997-58-1

Empirical Formula: C14H15N3O4

Molecular Weight: 289.29

MDL number: MFCD00065960

EINECS: 239-084-0

PRODUCT Properties

• Melting point: 168 °C (dec.)(lit.)
• alpha: -24 º (c=1 in 6 M HCl)
• Boiling point: 616.7±55.0 °C(Predicted)
• Density: 1.368±0.06 g/cm3(Predicted)
• refractive index: -23.5 ° (C=6, 6mol/L HCl)
• storage temp.: Sealed in dry,2-8°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• pka: 3.35±0.10(Predicted)
• form: powder to crystal
• color: White to Almost white
• optical activity: [α]20/D 24°, c = 1% in 6 M HCl
• Water Solubility: almost transparency
• BRN: 3561682
• Major Application: peptide synthesis
• InChI: 1S/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)/t12-/m0/s1
• InChIKey: WCOJOHPAKJFUDF-LBPRGKRZSA-N
• SMILES: OC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OCc2ccccc2
• CAS DataBase Reference: 14997-58-1(CAS DataBase Reference)

Description and Uses

Nα-Cbz-L-histidine is an N-Cbz-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• HS Code: 29332900
• Storage Class: 11 - Combustible Solids