rel-(1R,5S,6s)-tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate , 95% , 273206-92-1

CAS NO.：273206-92-1

Empirical Formula: C10H18N2O2

Molecular Weight: 198.27

MDL number: MFCD15111971

PRODUCT Properties

• Melting point: 45-47°
• Boiling point: 275℃
• Density: 1.144
• Flash point: 120℃
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• pka: 8.52±0.20(Predicted)
• Appearance: Off-white to yellow Solid
• InChI: InChI=1/C10H18N2O2/c1-10(2,3)14-9(13)12-4-6-7(5-12)8(6)11/h6-8H,4-5,11H2,1-3H3/t6-,7+,8+
• InChIKey: UWWZMHWHRBGMIT-JIGDXULJNA-N
• SMILES: N[C@@H]1[C@@]2([H])CN(C(=O)OC(C)(C)C)C[C@@]12[H] |&1:1,2,14,r|

Description and Uses

(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-Dimethylethyl Ester, is an intermediate in the preparation of a novel series of Histone Deacetylase (HDAC) Inhibitors, demonstrating class I selectivity and good oral bioavailability. It can also be used in the synthesis of Alatrofloxacin Mesylate (A511400).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H312-H332
• Precautionary statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
• HazardClass: IRRITANT
• HS Code: 2922390090