7-Benzyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine , 95% , 1059735-34-0

CAS NO.：1059735-34-0

Empirical Formula: C14H13Cl2N3

Molecular Weight: 294.18

MDL number: MFCD11846183

PRODUCT Properties

• Boiling point: 423.9±45.0 °C(Predicted)
• Density: 1.362
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• pka: 4.63±0.20(Predicted)
• Appearance: White to off-white Solid
• InChI: InChI=1S/C14H13Cl2N3/c15-13-11-6-7-19(8-10-4-2-1-3-5-10)9-12(11)17-14(16)18-13/h1-5H,6-9H2
• InChIKey: CTNDGYOJDNSZMQ-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC(Cl)=C2CCN(CC3=CC=CC=C3)CC2=N1

Description and Uses

7-Benzyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is used in preparation of heteroaryl compounds as PD-1/PD-L1 inhibitors for treatment of cancer.

Safety

• Symbol(GHS): GHS07
• Signal word: warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405