2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-delta-lactone , 95% , 32384-65-9

CAS NO.：32384-65-9

Empirical Formula: C18H42O6Si4

Molecular Weight: 466.87

MDL number: MFCD22665922

EINECS: 608-732-8

PRODUCT Properties

• Boiling point: 417℃
• Density: 0.97
• Flash point: 171℃
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
• form: Oil
• color: Colourless to Pale Yellow
• optical activity: 46.568°(C=0.01g/ml CHCL3)
• Stability: Moisture Sensitive
• InChI: InChI=1/C18H42O6Si4/c1-25(2,3)20-13-14-15(22-26(4,5)6)16(23-27(7,8)9)17(18(19)21-14)24-28(10,11)12/h14-17H,13H2,1-12H3/t14-,15-,16+,17-/s3
• InChIKey: VNGTZLYNGGLPIZ-NELUYGJANA-N
• SMILES: O([C@@H]1[C@H](C(=O)O[C@H](CO[Si](C)(C)C)[C@H]1O[Si](C)(C)C)O[Si](C)(C)C)[Si](C)(C)C |&1:1,2,6,13,r|

Description and Uses

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P271-P261-P280
• HS Code: 2931900090