(R)-1-(Naphthalen-1-yl)ethanamine hydrochloride , 98% , 82572-04-1

CAS NO.：82572-04-1

Empirical Formula: C12H14ClN

Molecular Weight: 207.699

MDL number: MFCD07369798

EINECS: 617-358-4

PRODUCT Properties

• Melting point: 253-257 °C(lit.)
• storage temp.: Sealed in dry,Room Temperature
• form: solid
• Appearance: White to off-white Solid
• optical activity: [α]/D 5.2±2°, c = 1 in methanol
• InChI: InChI=1/C12H13N.ClH/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11;/h2-9H,13H2,1H3;1H/t9-;/s3
• InChIKey: ZTNKTVBJMXQOBQ-OVMXBOEKNA-N
• SMILES: C1(=CC=CC2C=CC=CC1=2)[C@@H](C)N.Cl |&1:10,r|

Description and Uses

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335-H400
• Precautionary statements: P261-P273-P305+P351+P338
• Hazard Codes: Xn,N
• Risk Statements: 22-36/37/38-50
• Safety Statements: 26-60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 2