tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate , 97% , 289042-12-2

CAS NO.：289042-12-2

Empirical Formula: C29H40FN3O6S

Molecular Weight: 577.71

MDL number: MFCD08458343

EINECS: 1806241-263-5

PRODUCT Properties

• Melting point: 153-155°C
• Boiling point: 673.3±65.0 °C(Predicted)
• Density: 1.210
• storage temp.: Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: -0.43±0.10(Predicted)
• color: White to Off-White
• InChIKey: WIFPCEOJTKZGSA-UQECUQMJSA-N
• SMILES: O1[C@H](/C=C/C2=C(C(C)C)N=C(N(C)S(C)(=O)=O)N=C2C2=CC=C(F)C=C2)C[C@H](CC(OC(C)(C)C)=O)OC1(C)C
• CAS DataBase Reference: 289042-12-2(CAS DataBase Reference)

Description and Uses

(4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester (Rosuvastatin EP Impurity F) is a Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
• HS Code: 2935909550