(23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oicacid , 98% , 1662688-20-1

CAS NO.：1662688-20-1

Empirical Formula: C64H101N5O16

Molecular Weight: 1196.51

MDL number: MFCD34563738

PRODUCT Properties

• Boiling point: 1215.5±65.0 °C(Predicted)
• Density: 1.130±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO: Soluble: =10 mg/ml; Ethanol: Soluble: =10 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
• pka: 3.87±0.21(Predicted)
• form: Liquid (Density: 1.130±0.06 g/cm3)
• color: Colorless to light yellow
• InChIKey: COTQASXXEXJBOM-PJYGOTMFSA-N
• SMILES: C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)N[C@H](C(O)=O)CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O

Description and Uses

Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH (CAS 1662688-20-1, purity 99%), also known as the semaglutide side chain, is the core building block of the antidiabetic and weight-loss drug semaglutide. Semaglutide is a glucagon-like peptide-1 receptor (GLP-1R) agonist, primarily used for the treatment of type 2 diabetes, chronic weight management and the reduction of the risk of major cardiovascular events. It works by mimicking a natural hormone to suppress appetite, slow digestion and regulate blood glucose levels.

Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH is a useful compound in the chemical research.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338