4-Isoquinolineboronicacid , 98% , 192182-56-2

Synonym(s):
Isoquinolin-4-ylboronic acid;Isoquinoline-4-boronic acid

Update time: 2022-07-08

Melting point:	178°C
Boiling point:	419.1±37.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	2-8°C
form	solid
pka	4.61±0.30(Predicted)
color	White to off-white
InChI	1S/C9H8BNO2/c12-10(13)9-6-11-5-7-3-1-2-4-8(7)9/h1-6,12-13H
InChIKey	GDTOUTKTCGPAGY-UHFFFAOYSA-N
SMILES	OB(O)c1cncc2ccccc12
CAS DataBase Reference	192182-56-2(CAS DataBase Reference)

Reactant for:

Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases
Preparation of tetrabutylammonium trifluoroborates
Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain
Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines
Synthesis of antagonists of bacterial quorum sensing
Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338-P280a-P304+P340-P405-P501a
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39
WGK Germany	WGK 3
HazardClass	IRRITANT
HS Code	29349990
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3