BD9772331
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide , 97% , 757251-39-1
CAS NO.：757251-39-1
Empirical Formula: C13H12FN3O2
Molecular Weight: 261.25
MDL number: MFCD09033852
EINECS: 692-721-8
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB28.80 | In Stock |
|
| 1g | RMB72.80 | In Stock |
|
| 5g | RMB298.40 | In Stock |
|
| 10g | RMB548.80 | In Stock |
|
| 25g | RMB1291.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 143 °C |
| Boiling point: | 459.8±45.0 °C(Predicted) |
| Density | 1.305 |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 13.92±0.46(Predicted) |
| color | Orange to Dark Red to Brown |
| Water Solubility | 190mg/L at 20℃ |
| InChI | InChI=1S/C13H12FN3O2/c1-16-13(18)12-7-9(4-5-17-12)19-8-2-3-11(15)10(14)6-8/h2-7H,15H2,1H3,(H,16,18) |
| InChIKey | ZQHJPIPGBODVTG-UHFFFAOYSA-N |
| SMILES | C1(C(NC)=O)=NC=CC(OC2=CC=C(N)C(F)=C2)=C1 |
| LogP | 1.3 at 25℃ |
Description and Uses
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| HS Code | 2933.39.9200 |
