Home Categories Chemical Reagents Triethyl 4-phosphonocrotonate
F454821

Triethyl 4-phosphonocrotonate , Shunlian+transliteration, 94 , 10236-14-3

Synonym(s):
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester;4-Phosphonocrotonic acid triethyl ester

CAS NO.:10236-14-3

Empirical Formula: C10H19O5P

Molecular Weight: 250.23

MDL number: MFCD00009192

Pack Size Price Stock Quantity
10g RMB1018.40 In Stock
25g RMB1919.20 In Stock
250g RMB16324.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 135 °C0.4 mm Hg(lit.)
Density  1.128 g/mL at 25 °C(lit.)
refractive index  n20/D 1.455(lit.)
Flash point: >230 °F
storage temp.  Storage temp. 2-8°C
form  Liquid
color  Clear light yellow
InChI 1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+
InChIKey LXLODBXSCRTXFG-BQYQJAHWSA-N
SMILES CCOC(=O)\C=C\CP(=O)(OCC)OCC
CAS DataBase Reference 10236-14-3(CAS DataBase Reference)

Description and Uses

Reactant for:

  • Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
  • Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
  • Orally bioavailable GPR40 agonist synthesis
  • Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
  • Preaparation of mGlu4R agonists
  • Dearomatizing cyclization of nicotinyl-substituted esters and ketones

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29319090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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