LN-628730
3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one , 181525-38-2
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 145-148°C |
| Boiling point: | 437.4±55.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| vapor pressure | 0-0Pa at 20-25℃ |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 8.09±0.20(Predicted) |
| form | Solid |
| color | Beige |
| LogP | 0.19 at 20℃ and pH7 |
Description and Uses
9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is an intermediate in the synthesis of analog of Paliperidone, a combined serotonin and dopamine receptor antagonist.
Safety
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H412-H341-H302 |
| Precautionary statements | P273-P501-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501 |

![3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one](https://img.chemicalbook.com/CAS/GIF/181525-38-2.gif)


![9-(Benzyloxy)-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](https://img.chemicalbook.com/CAS/20180808/GIF/1008796-22-2.gif)
![3-ethyl-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one](https://img.chemicalbook.com/CAS/GIF/70381-47-4.gif)
![3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)](https://img.chemicalbook.com/CAS/GIF/260273-82-3.gif)

