![7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE](https://img.chemicalbook.com/CAS/GIF/6742-12-7.gif)
7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE , 97% , 6742-12-7
Synonym(s):
1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-(1S)-D-Ribitol;7-Amino-3-(β-D -ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine;8-Aza-9-deazaadenosine;Formycin;NSC 102811
PRODUCT Properties
| Melting point: | 141-144 °C (decomp) |
| Boiling point: | 709.5±60.0 °C(Predicted) |
| Density | 1.771±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: soluble1mg/mL |
| form | powder |
| pka | 8.37±0.50(Predicted) |
| color | white to off-white |
| BRN | 624229 |
Description and Uses
Formycin (Formycin A) is isolated from Nocardia interforma and from Streptomyces lavendulae , . The antibiotic is effective against Xanthomonas oryzae and Pellicularia filamentosa. Its activity against Yoshida rat sarcoma cell is enhanced by coformycin. Formycin B inhibits Xanthomonas oryzae and interferes with multiplication of influenza A virus in the cells of chick chorioallantoic membrane . Oxoformycin B shows no activity against Xanthomonas oryzae .
Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].
