LN-971332
4'-C-Fluoro-uridine , 98% HPLC , 1613589-24-4
Update time: 2023-04-23
PRODUCT Properties
Density | 1.77±0.1 g/cm3(Predicted) |
pka | 9.39±0.10(Predicted) |
form | Solid |
color | Off-white to yellow |
InChI | InChI=1S/C9H11FN2O6/c10-9(3-13)6(16)5(15)7(18-9)12-2-1-4(14)11-8(12)17/h1-2,5-7,13,15-16H,3H2,(H,11,14,17)/t5-,6+,7-,9-/m1/s1 |
InChIKey | RDCYLPRXPILMRP-JVZYCSMKSA-N |
SMILES | OC[C@@]1(F)O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O |
Description and Uses
EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3].