98% , 1675248-19-7

CAS NO.：1675248-19-7

Empirical Formula: C16H22N6O2

Molecular Weight: 330.39

MDL number:

PRODUCT Properties

• storage temp.: Storage temp. 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Solid
• color: Off-White to Pale Orange
• InChI: InChI=1/C16H22N6O2/c1-10-4-6-22(14(24)7-13(17)23)8-12(10)21(2)16-11-3-5-18-15(11)19-9-20-16/h3,5,9-10,12H,4,6-8H2,1-2H3,(H2,17,23)(H,18,19,20)/t10-,12+/s3
• InChIKey: CRDMXSMPTHMXRD-OMRPPZTANA-N
• SMILES: N([C@@H]1[C@@H](CCN(C(=O)CC(=O)N)C1)C)(C1N=CN=C2NC=CC=12)C |&1:1,2,r|

Description and Uses

Tofacitinib impurity L is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.