LN069189
Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) , ≥95% , 184179-08-6
CAS NO.：184179-08-6
Empirical Formula: C20H30N4O11
Molecular Weight: 502.47
MDL number: MFCD00671412
| Pack Size | Price | Stock | Quantity |
| 2mg | RMB3010.40 | In Stock |
|
| 5mg | RMB5032.80 | In Stock |
|
| 10mg | RMB8015.20 | In Stock |
|
| 25mg | RMB15032.80 | In Stock |
|
| 50mg | RMB25424.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 1021.1±65.0 °C(Predicted) |
| Density | 1.374±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: 1 mg/mL |
| form | powder |
| pka | 4.19±0.10(Predicted) |
| color | white |
| InChIKey | UMBVAPCONCILTL-JQTTWLCSNA-N |
| SMILES | [C@@H](CCC(=O)O)(NC(=O)[C@@H](NC(=O)C)CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C=O)CC(=O)O |&1:0,9,21,28,r| |
Description and Uses
A cell-permeable inhibitor of caspase-3. The C-terminal DEVD-CHO sequence of this peptide is a highly specific, potent, and reversible inhibitor of caspase-3 (Ki<1 nM) that has also been shown to strongly inhibit PARP cleavage in cultured human osteosarcoma cell extracts (IC50 = 200 pM). The N-terminal sequence (residues 1-16) corresponds to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF) and confers cell-permeability to the peptide.
Safety
| WGK Germany | 3 |
| Storage Class | 10 - Combustible liquids |
