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LN2934449

A-39183A , ≥98% , 79426-51-0

CAS NO.:79426-51-0

Empirical Formula: C34H30O10

Molecular Weight: 598.6

MDL number: MFCD33021109

Pack Size Price Stock Quantity
1mg RMB3520.00 In Stock
5mg RMB11432.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 790.1±60.0 °C(Predicted)
Density  1.509±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: soluble; DMSO: soluble; Ethanol: soluble
form  A solid
pka 3.36±0.60(Predicted)

Description and Uses

A-39183A is an active component of the A-39183 antibiotic complex produced by aerobic fermentation of Streptomyces NRRL 12049. It has activity against penicillin-resistant S. aureus 3055 and S. faecalis X66 (MICs = 32 and 32 μg/ml, respectively) and a variety of Gram-positive and Gram-negative anaerobic bacteria (MICs = 16-128 μg/ml) in an agar dilution assay.

A 39183A is a rare 9,9’-bianthryl antibiotic related to setomimycin isolated from a strain of Streptomyces by researchers at Eli Lilly, USA, in 1981. A 39183A has broad spectrum antibiotic activity against both susceptible and resistant isolates including many anaerobic species. The patent reported that A 38183A acts as an ionophore, aiding the partitioning of Mg+ and Ca+ ions into organic solvents and transport of ferric ions into mitochondria.