![Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)](https://img.chemicalbook.com/CAS/20211123/GIF/39916-28-4.gif)
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) , ≥98% , 39916-28-4
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB396.00 | In Stock |
|
| 10mg | RMB668.00 | In Stock |
|
| 50mg | RMB2296.00 | In Stock |
|
| 100mg | RMB4236.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | DMF: 20 mg/ml; DMSO: 14 mg/ml; Ethanol: 0.3 mg/ml; PBS (pH 7.2): Partially soluble |
| form | A crystalline solid |
Description and Uses
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging from 0.04 to 0.125 μM.2
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) generates lipid-based ROS and induce ferroptosis