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LN3569249

PtdIns-(3,4,5)-P3(1-stearoyl,2-arachidonoyl)(sodiumsalt) , ≥98%

CAS NO.:

Empirical Formula: C47H79Na7O22P4

Molecular Weight: 1280.94

MDL number: MFCD08056087

Pack Size Price Stock Quantity
50ug RMB832.00 In Stock
100ug RMB1592.00 In Stock
500ug RMB6724.00 In Stock
1mg RMB11432.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

solubility  CHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): Freely soluble

Description and Uses

PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and Akts are examples of PtdIns-(3,4,5)-P3-binding proteins.1,2 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 3 and 4.WARNING This product is not for human or veterinary use.