LN4237849
GW501516 , ≥98%
Synonym(s):
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid;GW1516
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB391.20 | In Stock |
|
| 10mM(in1mLDMSO) | RMB431.20 | In Stock |
|
| 10mg | RMB615.20 | In Stock |
|
| 50mg | RMB1511.20 | In Stock |
|
| 100mg | RMB2071.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 134 - 144°C |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
| InChI | InChI=1S/C21H20F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9,12,17H,10-11H2,1-2H3,(H,26,27) |
| InChIKey | JJSYBCYDXPXCHV-UHFFFAOYSA-N |
| SMILES | N1C(C)=C(SC=1C1=CC=C(C=C1)C(F)(F)F)CSC1C=CC(C(C)C=1)OCC(O)=O |
Description and Uses
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. GW 501516 has been found to enhance endurance in mice without any training.