LN4425649
PtdIns-(3,4,5)-P3(1-stearoyl,2-arachidonoyl)(sodiumsalt) , ≥98%
| Pack Size | Price | Stock | Quantity |
| 50ug | RMB944.00 | In Stock |
|
| 100ug | RMB1792.00 | In Stock |
|
| 500ug | RMB6776.00 | In Stock |
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| 1mg | RMB11516.00 | In Stock |
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| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| solubility | CHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): Freely soluble |
Description and Uses
PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and Akts are examples of PtdIns-(3,4,5)-P3-binding proteins.1,2 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 3 and 4.WARNING This product is not for human or veterinary use.