99% , 114301-97-2

CAS NO.：114301-97-2

Empirical Formula: C30H51N5O6

Molecular Weight: 577.76

MDL number: MFCD02259240

PRODUCT Properties

• storage temp.: −20°C
• solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 0.5 mg/ml
• form: A crystalline solid
• color: Yellow to orange
• InChIKey: GEZLBJRDZRUTOE-AHKZPQOWSA-N
• SMILES: C(N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC)(=O)CCCCCNC1C2C(C([N+]([O-])=O)=CC=1)=NON=2

Description and Uses

C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C6 ceramide in the inhibition of viral glycoprotein transport through the Golgi. C6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane. C6 NBD dihydro ceramide (d18:0/6:0) is structurally identical to C6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.

C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid[1].

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H319-H331-H336-H351-H361d-H372
• Precautionary statements: P201-P260-P264-P280-P304+P340+P311-P403+P233
• target organs: Central nervous system
• WGK Germany: 3
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3; toxic hazardous materials or hazardous materials causing chronic effects
• Hazard Classifications: Acute Tox. 3 Inhalation; Acute Tox. 4 Oral; Carc. 2; Eye Irrit. 2; Repr. 2; Skin Irrit. 2; STOT RE 1; STOT SE 3