LN5849848
97% , 11050-94-5
CAS NO.：11050-94-5
Empirical Formula: C45H72O12
Molecular Weight: 805.05
MDL number: MFCD32182608
EINECS: 234-275-5
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB398.40 | In Stock |
|
| 5mg | RMB1182.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 160-161℃ |
| Boiling point: | 911.4±65.0 °C(Predicted) |
| Density | 1.19 g/cm3 |
| storage temp. | −20°C |
| solubility | ≤30mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide |
| pka | 12.52±0.70(Predicted) |
| form | White to off-white powder. |
| color | White to off-white |
| Merck | 13,6902 |
Description and Uses
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin B is a nonselective inhibitor of the mitochondrial F1FO ATP synthase. Oligomycin B (1-10 μM) can reduce the rate of ATP depletion in myocardial ischemia and decrease calcium-induced calcium release oscillation frequency of rat sensory neurons.
Oligomycin B is an antibiotic that acts as a nonselective inhibitor of ATP synthase.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312 |
| Hazard Codes | Xn,T |
| Risk Statements | 20/21/22-68/20/21/22-22 |
| Safety Statements | 36/37 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | RK3330000 |
| F | 3-10 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29419090 |
