LN6629158
(±)-Lisofylline , ≥98% , 6493-06-7
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB972.00 | In Stock |
|
| 25mg | RMB1564.00 | In Stock |
|
| 50mg | RMB2988.00 | In Stock |
|
| 100mg | RMB5304.00 | In Stock |
|
| 250mg | RMB8223.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 123-125°C |
| Boiling point: | 511.2±56.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO: soluble |
| form | solid |
| pka | 15.22±0.20(Predicted) |
| color | white |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months. |
| InChI | InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3 |
| InChIKey | NSMXQKNUPPXBRG-UHFFFAOYSA-N |
| SMILES | N1(C)C2=C(N(C)C(=O)N(CCCCC(O)C)C2=O)N=C1 |
Description and Uses
Lisofylline (6493-06-7, racemic) displays anti-inflammatory activity. Regulates immune cell function and autoimmune response by inhibition of IL-12 signalling and cytokine production.1 Protects pancreatic beta cells and prevents type I diabetes in non-obese diabetic mice.2 Lisofylline reduces LPS-induced TNF alpha levels in CD-1 mice.3?Cell permeable.
A major oxidative metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.
Safety
| WGK Germany | 3 |
